Roosihermiatie B, Nishiyama M, Nakae K
The National Institute of Health System Research and Development Surabaya, Indonesia.
Southeast Asian J Trop Med Public Health. 2000 Mar;31(1):85-8.
Tuberculosis has been given great attention as HIV/AIDS has increased. Because HIV causes a higher tuberculosis risk is becoming more and more important better tuberculosis treatment. This study aimed to compare the smear conversion rate between short course therapy and the tuberculosis treatment with directly observed short course therapy (DOTS), in East Java, Indonesia. The average smear conversion rate in short course therapy among 35,292 cases was 94.40% over 5 year period (1989/90-1993/94). The tuberculosis treatment with DOTS was started in 1994/95. In the first 2 years the smear conversion rate were 97.67% (42/43) and 98.00% (196/200), respectively. The smear conversion rate of the treatment with DOTS was significantly higher compared to a short course therapy (p-value: <0.001). Thus, tuberculosis treatment with DOTS should be promoted. The concept of supervision by health workers or health cadres should be applied considering mostly are given by family members. And there should be readiness of tuberculosis staff to do the treatment with DOTS in all levels to expand the coverage.
随着艾滋病毒/艾滋病病例的增加，结核病受到了极大关注。由于艾滋病毒会导致更高的结核病风险，因此改善结核病治疗变得越来越重要。本研究旨在比较印度尼西亚东爪哇地区短程疗法与直接观察短程疗法（DOTS）治疗结核病的涂片转阴率。在5年期间（1989/90 - 1993/94），35292例采用短程疗法的患者平均涂片转阴率为94.40%。DOTS结核病治疗始于1994/95年。在最初的两年中，涂片转阴率分别为97.67%（42/43）和98.00%（196/200）。与短程疗法相比，DOTS治疗的涂片转阴率显著更高（p值：<0.001）。因此，应推广DOTS结核病治疗。考虑到大多数治疗是由家庭成员提供的，应采用卫生工作者或卫生干部监督的理念。各级结核病防治人员应做好开展DOTS治疗的准备，以扩大覆盖范围。
