Massari V J, Sanders-Bush E
Eur J Pharmacol. 1975 Sep-Oct;33(2):419-22. doi: 10.1016/0014-2999(75)90190-9.
In contrast to the pronounced fall in 5HT levels and synaptosomal uptake caused by p-chloroamphetamine, bilateral lesions of the B-9 cell group caused minimal regional changes, except for 35% decreases in the metathalamus-thalamus. We conclude therefore that the prolonged biochemical effects of p-chloroamphetamine are not due to a selective cytotoxic action on B-9 cells; and that a lateral 5HT pathway, possibly from the B-9 cell group, projects to the metathalamus-thalamus.
与对氯苯丙胺引起的5-羟色胺(5HT)水平显著下降和突触体摄取不同,B-9细胞群的双侧损伤仅引起最小的区域变化,除了丘脑后部-丘脑区域有35%的下降。因此,我们得出结论,对氯苯丙胺的长期生化作用并非由于对B-9细胞的选择性细胞毒性作用;并且一条可能来自B-9细胞群的外侧5HT通路投射至丘脑后部-丘脑。