苯丙胺对大鼠边缘前脑去甲肾上腺素能环磷酸腺苷生成系统的影响：其羟基化代谢产物的作用。 - Suppr

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超能文献

Modification of the noradrenergic cyclic AMP generating system in the rat limbic forebrain by amphetamine: role of its hydroxylated metabolites.

作者信息

Mobley P L, Sanders-Bush E, Smith H E, Sulser F

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1979 Apr;306(3):267-73. doi: 10.1007/BF00507113.

DOI:10.1007/BF00507113

PMID:224324

Abstract

摘要

相似文献

Modification of the noradrenergic cyclic AMP generating system in the rat limbic forebrain by amphetamine: role of its hydroxylated metabolites.苯丙胺对大鼠边缘前脑去甲肾上腺素能环磷酸腺苷生成系统的影响：其羟基化代谢产物的作用。

Naunyn Schmiedebergs Arch Pharmacol. 1979 Apr;306(3):267-73. doi: 10.1007/BF00507113.

Development of and recovery from subsensitivity of the noradrenergic cyclic AMP generating system in brain. Effect of amphetamine following inhibition of its aromatic hydroxylation by iprindole.脑中去甲肾上腺素能环磷酸腺苷生成系统的亚敏感性的发展及恢复。异吲哚抑制苯丙胺芳香羟化后苯丙胺的作用。

Naunyn Schmiedebergs Arch Pharmacol. 1980 Aug;313(2):113-8. doi: 10.1007/BF00498565.

The noradrenergic cyclic AMP generating system in the rat limbic forebrain and its stereospecificity for butaclamol.大鼠边缘前脑去甲肾上腺素能环磷酸腺苷生成系统及其对布他拉莫的立体特异性

J Pharm Pharmacol. 1976 Aug;28(8):645-6. doi: 10.1111/j.2042-7158.1976.tb02819.x.

Agonist effects of beta-phenethylamines on the noradrenergic cyclic adenosine 3',5'-monophosphate generating system in rat limbic forebrain. Stereoisomers of p-hydroxynorephedrine.β-苯乙胺对大鼠边缘前脑去甲肾上腺素能环磷酸腺苷生成系统的激动作用。对羟基去甲麻黄碱的立体异构体。

J Med Chem. 1977 Jul;20(7):978-81. doi: 10.1021/jm00217a028.

The noradrenergic cyclic AMP generating system in the limbic forebrain: pharmacological characterization in vitro and possible role of limbic noradrenergic mechanisms in the mode of action of antipsychotics.边缘前脑去甲肾上腺素能环磷酸腺苷生成系统：体外药理学特性及边缘去甲肾上腺素能机制在抗精神病药物作用方式中的可能作用

Eur J Pharmacol. 1976 Jun;37(2):357-66. doi: 10.1016/0014-2999(76)90043-1.

Structural and steric requirements for beta-phenethylamines as agonists of the noradrenergic cyclic AMP generating system in the rat limbic forebrain.β-苯乙胺作为大鼠边缘前脑去甲肾上腺素能环磷酸腺苷生成系统激动剂的结构和空间要求。

Naunyn Schmiedebergs Arch Pharmacol. 1978 Jun;303(2):175-80. doi: 10.1007/BF00508065.

Adaptive mechanisms of the noradrenergic cyclic AMP generating system in the limbic forebrain of the rat: adaptation to persistent changes in the availability of norepinephrine (NE).大鼠边缘前脑去甲肾上腺素能环磷酸腺苷生成系统的适应性机制：对去甲肾上腺素（NE）可利用性持续变化的适应。

J Neurochem. 1976 Sep;27(3):661-6. doi: 10.1111/j.1471-4159.1976.tb10391.x.

A possible common mechanism of action of antidepressant treatments: reduction in the sensitivity of the noradrenergic cyclic AMP gererating system in the rat limbic forebrain.抗抑郁治疗的一种可能的共同作用机制：降低大鼠边缘前脑去甲肾上腺素能环磷酸腺苷生成系统的敏感性。

Naunyn Schmiedebergs Arch Pharmacol. 1976 May;293(2):109-14. doi: 10.1007/BF00499215.

Cyclic AMP response to norepinephrine in the limbic forebrain of male and female rats: effect of desipramine.雄性和雌性大鼠边缘前脑对去甲肾上腺素的环磷酸腺苷反应：地昔帕明的作用。

Biochem Pharmacol. 1981 Nov 15;30(22):3126-8. doi: 10.1016/0006-2952(81)90506-2.

Effects of amphetamine and its hydroxylated metabolites on central noradrenergic mechanisms.安非他命及其羟基化代谢产物对中枢去甲肾上腺素能机制的影响。

J Pharmacol Exp Ther. 1973 Jun;185(3):620-32.

引用本文的文献

Self-stimulation and amphetamine: tolerance to d and l isomers and cross tolerance to cocaine and methylphenidate.自我刺激与苯丙胺：对d型和l型异构体的耐受性以及对可卡因和哌甲酯的交叉耐受性。

Psychopharmacology (Berl). 1981;74(1):23-8. doi: 10.1007/BF00431751.

Naunyn Schmiedebergs Arch Pharmacol. 1980 Aug;313(2):113-8. doi: 10.1007/BF00498565.

本文引用的文献

Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。

J Biol Chem. 1951 Nov;193(1):265-75.

Studies on sympathomimetic amines. II. The biotransformation and physiological disposition of d-amphetamine, d-p-hydroxyamphetamine and d-methamphetamine.拟交感神经胺类研究。II. d-苯丙胺、d-p-羟基苯丙胺和d-甲基苯丙胺的生物转化及生理处置

J Pharmacol Exp Ther. 1954 Mar;110(3):315-26.

The conversion in vivo of D-amphetamine to (+)-p-hydroxynorephedrine.体内D-苯丙胺向（+）-对羟基去甲麻黄碱的转化。

Biochim Biophys Acta. 1965 Aug 24;107(1):166-8. doi: 10.1016/0304-4165(65)90412-5.

Tissue concentrations of p-hydroxynorephedrine in rats injected with d-amphetamine: effect of pretreatment with desipramine.注射d-苯丙胺的大鼠体内对羟基去甲麻黄碱的组织浓度：地昔帕明预处理的影响

Life Sci. 1969 Jun 1;8(11):653-65. doi: 10.1016/0024-3205(69)90027-7.

A mechanism for the development of tolerance to amphetamine in rats.大鼠对苯丙胺产生耐受性的一种机制。

Psychopharmacologia. 1971;21(1):17-31. doi: 10.1007/BF00403992.

Effect of amphetamine on the pressor response to tyramine: formation of p-hydroxynorephedrine from amphetamine in man.苯丙胺对酪胺升压反应的影响：人体中苯丙胺形成对羟基去甲麻黄碱的过程。

Clin Pharmacol Ther. 1970 Sep-Oct;11(5):656-64. doi: 10.1002/cpt1970115656.

The metabolic fate of amphetamine in man and other species.安非他命在人类及其他物种中的代谢归宿。

Biochem J. 1970 Feb;116(3):425-35. doi: 10.1042/bj1160425.

Effects of amphetamine and its hydroxylated metabolites on central noradrenergic mechanisms.安非他命及其羟基化代谢产物对中枢去甲肾上腺素能机制的影响。

J Pharmacol Exp Ther. 1973 Jun;185(3):620-32.

Iprindole-amphetamine interactions in the rat: the role of aromatic hydroxylation of amphetamine in its mode of action.大鼠体内吲哚丙胺与苯丙胺的相互作用：苯丙胺芳香族羟基化在其作用方式中的作用。

J Pharmacol Exp Ther. 1972 Nov;183(2):307-15.

A protein binding assay for adenosine 3':5'-cyclic monophosphate.一种用于检测3':5'-环磷酸腺苷的蛋白质结合测定法。

Proc Natl Acad Sci U S A. 1970 Sep;67(1):305-12. doi: 10.1073/pnas.67.1.305.

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