Botzenhardt U, Lemmel E M
Folia Biol (Praha). 1975;21(4):280-2.
Tolerance to SRBC has been induced in adult mice by the aid of cyclophosphamide, and the duration of the tolerant state has been tested by a second injection of antigen at different times thereafter. As evidenced by 19S and 7S PFC 4 days after challenge, tolerance in this model is of relatively short duration and leads spontaneously to a memory state.
借助环磷酰胺已在成年小鼠中诱导出对绵羊红细胞(SRBC)的耐受性,并且通过在之后不同时间再次注射抗原来测试耐受状态的持续时间。如攻击后4天19S和7S空斑形成细胞(PFC)所证明的,该模型中的耐受性持续时间相对较短,并会自发地转变为记忆状态。