Portilla J, Boix V, Román F, Reus S, Merino E
Unit of Infectious Diseases, Hospital General Universitario de Alicante, Spain.
J Infect. 2000 Sep;41(2):182-4. doi: 10.1053/jinf.2000.0704.
Progressive multifocal leukoencephalopathy (PML) has been a devastating disease for HIV-1-infected patients since the beginning of the AIDS pandemic. Currently, highly active antiretroviral therapy (HAART) seems to improve the outcome of PML in many patients. We describe two cases of PML whose course worsened in spite of HAART, but had a good response to cidofovir.