针对法氏囊网状蛋白的抗血清。

Antiserum specific for reticulin of the bursa of fabricius.

作者信息

Boyd R L, Ward H A, Muller H K

出版信息

Int Arch Allergy Appl Immunol. 1976;50(1):129-32. doi: 10.1159/000231489.

Abstract

Antiserum produced by immunizing rabbits with embryonic chicken spleen cells showed, after appropriate absorption with cell suspensions, specificity for fetal spleen cells in membrane immunofluorescence tests. However, when the original antiserum was absorbed with tissue homogenates and tested on cryostat tissue sections, it reacted specifically with the reticular framework which separates the cortical and medullary lymphocytes in the follicles of the adult bursa of Fabricius. It is suggested that the reticulin may influence bursal lymphoid differentiation.

摘要

用鸡胚脾细胞免疫家兔产生的抗血清，经细胞悬液适当吸收后，在膜免疫荧光试验中对胎儿脾细胞显示出特异性。然而，当原始抗血清用组织匀浆吸收并在低温恒冷箱组织切片上进行检测时，它与在成年法氏囊滤泡中分隔皮质和髓质淋巴细胞的网状结构发生特异性反应。有人认为，网状纤维可能影响法氏囊淋巴样分化。