Baba T, Nishida S, Mitsui M
Comp Immunol Microbiol Infect Dis. 1983;6(4):333-8. doi: 10.1016/0147-9571(83)90026-7.
Antisera to bursal extracts or perfusates were prepared and the influence of such sera on antibody production in chickens was investigated by the injection of antisera during the embryonic stage. Antisera to cyclophosphamide treated bursal extracts or bursal perfusates were injected on the 15th day of embryogenesis. The level of antibodies produced by chickens treated by these antisera was equal to the controls but IgG antibodies were totally absent. These results suggested that the administration of these antisera inhibited the differentiation of IgM antibody producing cells.
制备了针对法氏囊提取物或灌注液的抗血清，并通过在胚胎期注射抗血清来研究此类血清对鸡抗体产生的影响。在胚胎发育的第15天注射针对环磷酰胺处理的法氏囊提取物或法氏囊灌注液的抗血清。经这些抗血清处理的鸡产生的抗体水平与对照组相当，但完全没有IgG抗体。这些结果表明，给予这些抗血清会抑制产生IgM抗体的细胞的分化。
