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一名儿童同时感染非典型分枝杆菌和结核分枝杆菌导致颈部淋巴结病

Dual infection with atypical mycobacteria and Mycobacterium tuberculosis causing cervical lymphadenopathy in a child.

作者信息

Ganesan S, Thirlwall A, Brewis C, Grant H R, Novelli V M

机构信息

Department of Otolaryngology, Royal National Throat, Nose and Ear Hospital, London, UK.

出版信息

J Laryngol Otol. 2000 Aug;114(8):649-51. doi: 10.1258/0022215001906426.

Abstract

The most common presentation of mycobacterial infection encountered in otolaryngological practice is cervical lymphadenitis. We report a child with an unusual cause of cervical lymphadenopathy, i.e. dual tuberculous infections. This had clinical ramifications as, initially Mycobacterium avium-intracellulare was grown in culture and was resistant to standard anti-tuberculous agents, and hence treated with excision of the lymph node. However, the cultures from the excised lymph node grew out Mycobacterium tuberculosis that was sensitive to standard anti-tuberculous drugs. To our knowledge, no such presentation has been reported previously. We also review the literature on cervical lymphadenitis due to atypical mycobacteria and Mycobacterium tuberculosis, with particular emphasis on clinical presentation, diagnosis and management.

摘要

在耳鼻喉科临床实践中,分枝杆菌感染最常见的表现是颈部淋巴结炎。我们报告了一名儿童颈部淋巴结病的不寻常病因,即双重结核感染。这产生了临床影响,最初在培养物中培养出鸟分枝杆菌复合群,且对标准抗结核药物耐药,因此通过切除淋巴结进行治疗。然而,切除的淋巴结培养物中生长出对标准抗结核药物敏感的结核分枝杆菌。据我们所知,此前尚无此类表现的报道。我们还回顾了关于非典型分枝杆菌和结核分枝杆菌所致颈部淋巴结炎的文献,特别强调了临床表现、诊断和管理。

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