Zatik J, Aranyosi J, Fülesdi B
Debreceni Egyetem Orvos- és Egészségtudományi Centrum, Altalános Orvostudományi Kar, Szülészeti és Nógyógyászati Klinika.
Orv Hetil. 2000 Sep 24;141(39):2123-6.
Clinical and pathophysiological aspects of preeclampsia and eclampsia have been found to be responsible for the majority of maternal mortality, but the exact role of them is still unknown. It is conceivable that altered cerebral hemodynamics and autoregulation is responsible for the neurological complications. The background of the cerebral processes is still not clarified. Authors summarize the changes of cerebral circulation which develop during preeclampsia and explanations for cerebral hemodynamic alterations during normal, preeclamptic and exclamptic pregnancies are discussed. They conclude that there is no accurate method for predicting eclampsia. Cerebral hemodynamical studies are only helpful in better understanding the pathophysiological background of preeclampsia-eclampsia syndrome at present.
子痫前期和子痫的临床及病理生理方面已被发现是导致大多数孕产妇死亡的原因,但其确切作用仍不清楚。可以想象,脑血流动力学和自动调节的改变是神经并发症的原因。大脑过程的背景仍未阐明。作者总结了子痫前期期间发生的脑循环变化,并讨论了正常、子痫前期和子痫期妊娠期间脑血流动力学改变的原因。他们得出结论,目前尚无准确的方法预测子痫。目前,脑血流动力学研究仅有助于更好地理解子痫前期-子痫综合征的病理生理背景。