Hedström M, Svensson J, Dalén N
Department of Orthopaedics, Karolinska Institutet, Danderyd Hospital, Sweden.
Acta Orthop Scand. 2000 Aug;71(4):409-13. doi: 10.1080/000164700317393439.
Biochemical markers of bone formation and bone resorption were measured preoperatively, within 18 hours after a hip fracture (n 106) and bone mineral density (BMD) was measured with quantitative computer tomography (QCT), dual-energy x-ray absorptiometry (DXA) and heel ultrasound in 63 hip fracture patients. Patients with pertrochanteric fractures had more osteoporosis in all measurements than patients with femoral neck fractures. We found no differences in biochemical markers of bone formation or bone resorption in patients with femoral neck fractures and in those with pertrochanteric fractures. Correlations between biochemical bone markers and bone density, bone mass and stiffness on admission were weak.
术前测量了骨形成和骨吸收的生化标志物，在髋部骨折后18小时内对106例患者进行了测量，并对63例髋部骨折患者采用定量计算机断层扫描（QCT）、双能X线吸收法（DXA）和足跟超声测量了骨矿物质密度（BMD）。转子间骨折患者在所有测量中比股骨颈骨折患者有更多的骨质疏松症。我们发现股骨颈骨折患者和转子间骨折患者在骨形成或骨吸收的生化标志物方面没有差异。入院时生化骨标志物与骨密度、骨量和硬度之间的相关性较弱。
