Sato M, Ishida H, Konno K, Naganuma H, Hamashima Y, Komatsuda T, Ishida J, Watanabe S
First Department of Internal Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Abdom Imaging. 2000 Nov-Dec;25(6):596-601. doi: 10.1007/s002610000070.
Liver tumors are a relatively rare pathologic condition in children and young patients. The aim of the present study was to categorize the sonographic (US) and color Doppler results of liver tumors in these patients.
We retrospectively reviewed the US findings of 23 such cases: malignant tumor (13 cases)-hepatoblastoma (four cases), hepatocellular carcinoma (HCC; four cases), and hepatic metastasis (five cases); benign tumor (10 cases)-hepatocellular adenoma (four cases), focal nodular hyperplasia (two cases), mesenchymal hamartoma (two cases), cystadenoma (one case), and hemangioendothelioma (one case).
There was no specific US findings for each tumor type. HCC usually developed on a normal liver and was imaged as multiple nodules. Color Doppler US helped in differentiating multiple metastatic nodules (hypovascular) from multiple HCC nodules (hypervascular). Presence of intratumoral cystic areas was usually suggestive of benign tumors. Follow-up US was useful for detecting small nodules in high-risk groups (congenital biliary atresia, glycogen storage disease). Color Doppler US helped in diagnosing portal thrombus or intratumoral shunt.
Although there were no highly specific findings, US and color Doppler results contributed, to a certain degree, to the diagnosis of liver tumors in children and young adults by showing intratumoral cystic areas or vascularity.
肝肿瘤在儿童和年轻患者中是一种相对罕见的病理状况。本研究的目的是对这些患者肝肿瘤的超声（US）及彩色多普勒检查结果进行分类。
我们回顾性分析了23例此类病例的超声检查结果：恶性肿瘤（13例）——肝母细胞瘤（4例）、肝细胞癌（HCC；4例）和肝转移瘤（5例）；良性肿瘤（10例）——肝细胞腺瘤（4例）、局灶性结节性增生（2例）、间叶性错构瘤（2例）、囊腺瘤（1例）和血管内皮瘤（1例）。
每种肿瘤类型均无特异性超声表现。HCC通常发生于正常肝脏，表现为多个结节。彩色多普勒超声有助于鉴别多发转移瘤结节（低血供）和多发HCC结节（高血供）。肿瘤内出现囊性区域通常提示为良性肿瘤。超声随访有助于检测高危组（先天性胆道闭锁、糖原贮积病）中的小结节。彩色多普勒超声有助于诊断门静脉血栓或肿瘤内分流。
尽管没有高度特异性的表现，但超声及彩色多普勒检查结果通过显示肿瘤内囊性区域或血管情况，在一定程度上有助于儿童和年轻成人肝肿瘤的诊断。
