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软骨肿瘤:评估与治疗

Cartilage tumors: evaluation and treatment.

作者信息

Marco R A, Gitelis S, Brebach G T, Healey J H

机构信息

M.D. Anderson Cancer Center, Houston, USA.

出版信息

J Am Acad Orthop Surg. 2000 Sep-Oct;8(5):292-304. doi: 10.5435/00124635-200009000-00003.

DOI:10.5435/00124635-200009000-00003
PMID:11029557
Abstract

The proper treatment of cartilaginous tumors is dependent on the clinicopathologic and radiologic findings. Enchondroma is a benign tumor that is usually asymptomatic and thus should be treated nonoperatively. Symptomatic enchondromas are often treated by intralesional excision. Intramedullary low-grade chondrosarcoma is a malignant tumor that is usually painful. The treatment of low-grade chondrosarcoma may range from intralesional excision with or without adjuvant therapy to wide excision. Although intralesional excisions have a higher bone and joint preservation rate than wide excisions, they may be associated with a higher local recurrence rate. Intermediate- and high-grade chondrosarcomas are treated with wide excisions. The treatment of these cartilaginous lesions should involve a multidisciplinary team including a musculoskeletal surgeon, a radiologist, and a pathologist.

摘要

软骨肿瘤的恰当治疗取决于临床病理和影像学检查结果。内生软骨瘤是一种通常无症状的良性肿瘤,因此应采取非手术治疗。有症状的内生软骨瘤常采用病灶内切除治疗。髓内低度软骨肉瘤是一种通常会引起疼痛的恶性肿瘤。低度软骨肉瘤的治疗方法可从伴有或不伴有辅助治疗的病灶内切除到广泛切除。尽管病灶内切除比广泛切除具有更高的骨和关节保留率,但它们可能与更高的局部复发率相关。中高度软骨肉瘤采用广泛切除治疗。这些软骨病变的治疗应包括一个多学科团队,成员包括肌肉骨骼外科医生、放射科医生和病理科医生。

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