Streitbuerger A, Hardes J, Gebert C, Ahrens H, Winkelmann W, Gosheger G
Klinik und Poliklinik für allgemeine Orthopädie, Universitätsklinikum Münster, Albert-Schweitzer-Strasse 33, 48149 Münster.
Orthopade. 2006 Aug;35(8):871-81; quiz 882. doi: 10.1007/s00132-006-0991-1.
Primary malignant bone tumours are rare. The annual incidence of these tumours is 10 per 1 million. Nearly 30% of the primary malignant bone tumours are malignant cartilage tumours. The frequency of benign cartilage tumours cannot be definitely estimated because these tumours are normally clinically inapparent and therefore often diagnosed as an incidental finding. The cartilage tumours appear as benign lesions (e.g. chondroma), as borderline tumours (proliferative chondroma vs grade I chondrosarcoma) or as highly malignant chondrosarcoma (e.g. dedifferentiated chondrosarcoma). Commensurate with the different clinical and oncological manifestations of the cartilage tumours, there are wide differences in the treatment and clinical course of the individual tumour. This article discusses the problems in the diagnosis and treatment of cartilage tumours from an orthopaedic point of view.
原发性恶性骨肿瘤较为罕见。这些肿瘤的年发病率为每100万人中有10例。近30%的原发性恶性骨肿瘤是恶性软骨肿瘤。良性软骨肿瘤的发生率难以确切估计，因为这些肿瘤通常在临床上无明显症状，因此常作为偶然发现被诊断出来。软骨肿瘤可表现为良性病变（如软骨瘤）、交界性肿瘤（增殖性软骨瘤与Ⅰ级软骨肉瘤）或高度恶性的软骨肉瘤（如去分化软骨肉瘤）。与软骨肿瘤不同的临床和肿瘤学表现相对应，各个肿瘤的治疗方法和临床病程差异很大。本文从骨科角度探讨软骨肿瘤的诊断和治疗问题。
