Matsuda M, Yoshimoto M, Iwase T, Takahashi K, Kasumi F, Akiyama F, Sakamoto G
Department of Breast Surgery, Cancer Institute Hospital, Mitaka, Japan.
Breast Cancer. 2000 Jan;7(1):65-70. doi: 10.1007/BF02967190.
We attempted to improve the effectiveness of diagnostic techniques in mammographic imaging of mucinous carcinoma of the breast by defining the characteristics of mammographic images and investigating correlations between these images and various clinicopathological findings.
Clinicopathological investigations of 92 lesions in 90 cases of mucinous carcinoma of the breast were made. Mammography demonstrated 80 lesions with identical tumor shadow characteristics and these were divided into three patterns, circumscribed, indistinct and blended. Correlations between clinicopathological findings and mammographic images were investigated.
Patients with mucinous carcinoma of the breast usually present with a palpable mass. The lymph node metastasis rate in this study was low and prognosis in the early postoperative period was satisfactory. On mammograms, the circumscribed pattern was the most frequent. The investigation of the correlation between histological sub-type and mammographic pattern showed a high percentage of pure type lesions exhibited in the circumscribed pattern while those of mixed histologic type often showed the indistinct pattern. Calcification frequency demonstrated on mammography was 75% for the indistinct and mixed patterns, and approximately 50% for the circumscribed pattern. A high rate of calcification seen outside the tumor shadow suggested a high frequency of invasion and the spread of cancer to neighboring tissues. The circumscribed pattern was least frequently associated with lymph node metastasis, followed by the indistinct and blended patterns in that order.
Investigation of clinicopathological factors and mammographic findings in mucinous carcinoma of the breast suggests that mammography provides clinically valuable information for the treatment of this disease. These findings indicate the importance of careful mammographic observation at the time of diagnosis.
我们试图通过界定乳腺黏液癌钼靶图像的特征，并研究这些图像与各种临床病理表现之间的相关性，来提高钼靶成像对乳腺黏液癌的诊断技术有效性。
对90例乳腺黏液癌患者的92个病灶进行了临床病理研究。钼靶检查显示80个病灶具有相同的肿瘤阴影特征，这些病灶被分为三种类型：边界清晰型、边界不清型和融合型。研究了临床病理表现与钼靶图像之间的相关性。
乳腺黏液癌患者通常表现为可触及的肿块。本研究中的淋巴结转移率较低，术后早期预后良好。在钼靶片上，边界清晰型最为常见。组织学亚型与钼靶类型之间的相关性研究表明，边界清晰型中纯型病灶的比例较高，而混合组织学类型的病灶通常表现为边界不清型。钼靶检查显示的钙化频率在边界不清型和混合型中为75%，在边界清晰型中约为50%。肿瘤阴影外出现的高钙化率提示癌症侵犯和扩散至邻近组织的频率较高。边界清晰型与淋巴结转移的相关性最低，其次是边界不清型和融合型。
对乳腺黏液癌临床病理因素和钼靶表现的研究表明，钼靶检查为该疾病的治疗提供了有临床价值的信息。这些发现表明在诊断时进行仔细钼靶观察的重要性。
