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慢性脊髓损伤中的睡眠呼吸暂停综合征:相关因素与治疗

Sleep apnea syndrome in chronic spinal cord injury: associated factors and treatment.

作者信息

Burns S P, Little J W, Hussey J D, Lyman P, Lakshminarayanan S

机构信息

Department of Rehabilitation Medicine, University of Washington, Seattle, USA.

出版信息

Arch Phys Med Rehabil. 2000 Oct;81(10):1334-9. doi: 10.1053/apmr.2000.9398.

Abstract

OBJECTIVE

To determine the prevalence of sleep apnea in a sample of persons with chronic spinal cord injury (SCI) of varying injury levels and degrees of impairment.

DESIGN

Cross-sectional study.

SETTING

Inpatient SCI rehabilitation unit.

PARTICIPANTS

Twenty men with SCI (motor complete and incomplete; American Spinal Injury Association classes A-D) of at least 1 year's duration, randomly selected from patients with SCI undergoing elective hospitalization.

MAIN OUTCOME MEASURES

Apnea index, determined by sleep study (including chest wall movement, airflow, oxygen saturation), and daytime sleepiness, determined by Epworth sleepiness score.

RESULTS

Eight subjects (40%) had sleep apnea, manifested by elevated apnea index (mean +/- SD, 17.1 +/- 6.9) and excessive daytime sleepiness. Sleep apnea was commonly diagnosed in motor-incomplete injuries. A trend (p = .07) existed toward a greater prevalence of sleep apnea with tetraplegia. Age and body mass index were not associated with sleep apnea.

CONCLUSION

The prevalence of sleep apnea in men with chronic SCI admitted for nonrespiratory elective hospitalization is high relative to the general population.

摘要

目的

确定不同损伤水平和损伤程度的慢性脊髓损伤(SCI)患者样本中睡眠呼吸暂停的患病率。

设计

横断面研究。

地点

住院SCI康复科。

参与者

20名患有SCI(运动完全性和不完全性;美国脊髓损伤协会A - D级)且病程至少1年的男性,从接受择期住院治疗的SCI患者中随机选取。

主要观察指标

通过睡眠研究(包括胸壁运动、气流、血氧饱和度)确定呼吸暂停指数,通过爱泼华嗜睡量表确定日间嗜睡情况。

结果

8名受试者(40%)患有睡眠呼吸暂停,表现为呼吸暂停指数升高(均值±标准差,17.1±6.9)和日间过度嗜睡。睡眠呼吸暂停在运动不完全性损伤中常见。四肢瘫痪患者睡眠呼吸暂停患病率有升高趋势(p = 0.07)。年龄和体重指数与睡眠呼吸暂停无关。

结论

因非呼吸相关择期住院的慢性SCI男性患者中,睡眠呼吸暂停的患病率相对于普通人群较高。

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