Degtyarenko A M, Kaufman M P
Division of Cardiovascular Medicine, Departments of Internal Medicine and Human Physiology, TB 172, University of California, Davis, CA 95616, USA.
Brain Res. 2000 Oct 13;880(1-2):178-82. doi: 10.1016/s0006-8993(00)02738-4.
We found that electrical stimulation of the mesencephalic locomotor region (MLR) inhibited the discharge of deep dorsal horn neurons receiving group III afferent input from the triceps surae muscles. In contrast, contraction of these muscles induced by electrical stimulation of the tibial nerve activated these dorsal horn neurons. Our findings show that descending central motor commands can inhibit dorsal horn interneurons receiving input from group III afferents during exercise.
我们发现,对中脑运动区(MLR)进行电刺激会抑制接受来自腓肠肌Ⅲ类传入输入的背角深层神经元的放电。相反,通过电刺激胫神经诱导这些肌肉收缩会激活这些背角神经元。我们的研究结果表明,下行的中枢运动指令在运动过程中可抑制接受Ⅲ类传入输入的背角中间神经元。