Davis E A, Lindstrom R L
Phillips Eye Institute, Minneapolis, Minnesota, USA.
J Cataract Refract Surg. 2000 Oct;26(10):1505-9. doi: 10.1016/s0886-3350(00)00436-3.
To determine whether differences exist in visual acuity and corneal thickness after phacoemulsification using various viscoelastic substances.
Phillips Eye Institute, Minneapolis, Minnesota, USA.
Fifty patients having routine phacoemulsification cataract extraction and intraocular lens implantation by a single surgeon using the same technique were randomly assigned to receive intraoperative administration of 1 of 3 viscoelastic substances: Amvisc Plus(R) (sodium hyaluronate 1.6%), OcuCoat(R) (hydroxypropyl methylcellulose 2%), or Viscoat(R) (chondroitin sulfate 4%-sodium hyaluronate 3%). Visual acuity and corneal thickness on the first postoperative day were compared between groups.
Patients with a best corrected visual acuity (BCVA) of 20/40 or better 1 day postoperatively had significantly thinner corneas (596 microm) than those with a BCVA worse than 20/40 (639 microm). There were no differences in postoperative BCVA or percentage increase in central corneal pachymetry among the 3 viscoelastic groups.
Viscoat, Amvisc Plus, and OcuCoat were comparable in their ability to produce clear corneas and good vision after routine phacoemulsification.
确定使用不同粘弹剂进行超声乳化术后视力和角膜厚度是否存在差异。
美国明尼苏达州明尼阿波利斯市菲利普斯眼科研究所。
50例由同一位外科医生采用相同技术进行常规超声乳化白内障摘除及人工晶状体植入术的患者被随机分配,术中给予3种粘弹剂中的1种:Amvisc Plus(1.6%透明质酸钠)、OcuCoat(2%羟丙基甲基纤维素)或Viscoat(4%硫酸软骨素 - 3%透明质酸钠)。比较各组术后第1天的视力和角膜厚度。
术后1天最佳矫正视力(BCVA)为20/40或更好的患者角膜明显更薄(596微米),而BCVA低于20/40的患者角膜厚度为639微米。3种粘弹剂组术后BCVA或中央角膜测厚增加百分比无差异。
在常规超声乳化术后,Viscoat、Amvisc Plus和OcuCoat在产生透明角膜和良好视力方面的能力相当。