Suppr超能文献

无症状性乳糜泻与克罗恩病的关联

[Association of asymptomatic celiac disease and Crohn's disease].

作者信息

Karoui S, Boubaker J, Hamzaoui S, Ben Yaghlene L, Filali A

机构信息

Service de Gastro-Entérologie A, Hôpital La Rabta, 1007 Tunis, Tunisie.

出版信息

Ann Med Interne (Paris). 2000 Sep;151(5):411-2.

Abstract

A 24-year-old woman had Crohn's colitis which had been diagnosed in 1997. The patient was given sulfazalazine and responded well. Antiendomysial and antigliadin antibodies were positive. Diagnosis of celiac disease was confirmed by duodenal biopsy showing villous atrophy and an increased number of lymphocytes infiltrating the epithelium. Few cases associating Crohn's disease and celiac disease have been reported. This case illustrates the complexity of the pathogenic mechanisms in these two disease. Our patient required a gluten-free diet although the celiac disease was asymptomatic, basically to avoid the risk of malignancy associated with celiac disease.

摘要

一名24岁女性于1997年被诊断为克罗恩结肠炎。患者接受柳氮磺胺吡啶治疗,反应良好。抗肌内膜抗体和抗麦醇溶蛋白抗体呈阳性。十二指肠活检显示绒毛萎缩且上皮内淋巴细胞浸润数量增加,从而确诊为乳糜泻。报道的克罗恩病与乳糜泻相关的病例很少。该病例说明了这两种疾病致病机制的复杂性。尽管患者的乳糜泻没有症状,但仍需无麸质饮食,主要是为了避免与乳糜泻相关的恶性肿瘤风险。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验