Cheikh Imed, Maamouri Nadia, Chouaib Soufiène, Chaabouni Hatem, Ouerghi Hajer, Ben Ammar Ahmed
Service de Gastro-entérologie B, EPS La Rabta, Tunis.
Tunis Med. 2003 Dec;81(12):969-71.
Crohn's disease and celiac disease are two chronic digestive diseases. The pathological mechanisms that lead to them are not known. Their association is rare leading to diagnostic and etiopathogenic problems. The aim of this study is to report clinical, endoscopical and histopathological characteristics of this association and to discuss the etiopathogenic links between these two diseases. The association of celiac disease and Crohn's disease is possible although rare. Many etiopathological mechanisms were suggested to explain such an association. In the case of celiac disease, the association with Crohn's disease is suggested by the characteristics of the diarrhea, the anoperineal lesions and will be confirmed by ileocolonoscopy and biopsy. In contrary, the diagnosis of celiac disease associated with Crohn's disease is frequently suggested by the endoscopy of upper gastrointestinal tract systematically practiced and will be confirmed by biopsy and serological celiac disease tests.
克罗恩病和乳糜泻是两种慢性消化系统疾病。导致它们的病理机制尚不清楚。它们的关联很罕见，会引发诊断和病因学方面的问题。本研究的目的是报告这种关联的临床、内镜和组织病理学特征，并讨论这两种疾病之间的病因学联系。乳糜泻和克罗恩病的关联虽罕见但有可能。人们提出了许多病因学机制来解释这种关联。就乳糜泻而言，腹泻、肛门直肠病变的特征提示其与克罗恩病有关联，这将通过回结肠镜检查和活检得到证实。相反，与克罗恩病相关的乳糜泻诊断常常通过系统进行的上消化道内镜检查提示，并将通过活检和乳糜泻血清学检测得到证实。
