胃抑肽：对体外分离的大鼠胰岛中葡萄糖诱导的胰岛素释放的影响。
Gastric inhibitory polypeptide: effect on glucose-induced insulin release from isolated rat pancreatic islets in vitro.
作者信息
Schauder P, Brown J C, Frerichs H, Creutzfeldt W
出版信息
Diabetologia. 1975 Oct;11(5):483-4. doi: 10.1007/BF00429919.
PMID:1103369
Abstract
Gastric Inhibitory Polypeptide (GIP; 1 or 10 mug/ml) potentiated glucose-induced (8 or 16.6 mM) insulin (IRI) release from isolated rat pancreatic islets. Basal release was unaffected. The threshold concentration of glucose necessary for GIP to modulate IRI release was between 6 and 8 mM. GIP had no effect on IRI release from islets submitted to a maximal glucose stimulus (25 mM).
摘要
胃抑制多肽（GIP；1或10微克/毫升）增强了葡萄糖诱导（8或16.6毫摩尔）的胰岛素（IRI）从分离的大鼠胰岛中的释放。基础释放不受影响。GIP调节IRI释放所需的葡萄糖阈值浓度在6至8毫摩尔之间。GIP对接受最大葡萄糖刺激（25毫摩尔）的胰岛的IRI释放没有影响。
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