Trisolini R, Dore R, Biagi F, Luinetti O, Pochetti P, Carrabino N, Luisetti M
Clinica di Malattie dell'Apparato Respiratorio, Università di Pavia, Italy.
Sarcoidosis Vasc Diffuse Lung Dis. 2000 Oct;17(3):288-91.
Mesalamine-induced lung toxicity has often been described. We report on a case of a patient who underwent mesalamine treatment, though in the absence of established criteria required for diagnosing Crohn's disease (CD) or ulcerative colitis (UC). He developed an adverse respiratory reaction to the drug, thus definitely proving its lung damaging capacity. The clinical presentation included eosinophilic pleural effusion, a feature never previously described in association with mesalamine intake.
美沙拉嗪诱发的肺部毒性屡有报道。我们报告一例接受美沙拉嗪治疗的患者，尽管其不符合诊断克罗恩病（CD）或溃疡性结肠炎（UC）所需的既定标准。他对该药产生了不良呼吸反应，从而明确证实了其肺损伤能力。临床表现包括嗜酸性胸腔积液，这是以前从未与服用美沙拉嗪相关联描述过的特征。
