Büngener W
Tropenmed Parasitol. 1975 Sep;26(3):285-90.
Trypanosoma musculi brought into Plasmodium berghei-infected mice in the later stages of the malaria infection shows rapid, approximately logarithmic multiplication in the peripheral blood. The trypanosome number increases by a factor of 2-9 per day, multiplication of the parasites kills most mice in a few days. Many multiplicative forms of the trypanosomes and a few trypanosomes without nuclei are seen in blood smears. Histologically and in touch preparations, masses of multiplicative forms of the trypanosomes are seen in the sinusoids of the liver. Aggregates of trypanosomes are found, too, in the kidney medulla and, inconstantly, in venous sinuses of the spleen and postcapillary venules of lymph nodes. Occasionally, trypanosomes may be found extravascularly in the interstitial connective tissue especially of the pancreas, in lymph vessels and lymph node sinuses. - Mice infected in earlier stages of the Plasmodium berghei infection achieve stabilization of trypanosome numbers.
在疟疾感染后期将鼠锥虫引入感染伯氏疟原虫的小鼠体内，鼠锥虫在外周血中呈现快速、近似对数的增殖。锥虫数量每天增加2至9倍，寄生虫的增殖在几天内杀死大多数小鼠。在血涂片中可见许多增殖型锥虫和一些无核锥虫。在组织学检查和触片标本中，在肝脏的血窦中可见大量增殖型锥虫。在肾髓质中也发现了锥虫聚集物，偶尔在脾脏静脉窦和淋巴结毛细血管后微静脉中也能发现。偶尔，锥虫可能在血管外，特别是在胰腺的间质结缔组织、淋巴管和淋巴结窦中被发现。 - 在伯氏疟原虫感染早期阶段感染的小鼠，锥虫数量会趋于稳定。
