Lefèvre P, Gilot P, Godiscal H, Content J, Fauville-Dufaux M
Department of Virology, Pasteur Institute, Brussels, Belgium.
Diagn Microbiol Infect Dis. 2000 Oct;38(2):127-9. doi: 10.1016/s0732-8893(00)00169-3.
We report a case of recurrent granulomatous tenosynovitis with M. intracellulare in a 55-year-old HIV negative diabetic woman. Identification of the causative agent further than belonging to the M. avium-intracellulare complex is provided by specific PCR-amplification of genomic DNA and sequencing of an hypervariable region within its 16S RNA gene. Sixteen months antibiotic regimen of rifabutin and clarithromycin led to a complete resolution of the tenosynovitis.
我们报告了一例55岁HIV阴性糖尿病女性复发性肉芽肿性腱鞘炎合并胞内分枝杆菌感染的病例。通过对基因组DNA进行特异性PCR扩增以及对其16S RNA基因内的一个高变区进行测序，确定了病原体，其病原体不仅仅属于鸟分枝杆菌-胞内分枝杆菌复合群。利福布汀和克拉霉素的16个月抗生素治疗方案使腱鞘炎完全消退。
