Springer N S, Fricke N L
Am J Ment Defic. 1975 Nov;80(3):317-22.
Literature relevant to drugs reported as affecting or not affecting nutrient metabolism and diet for developmentally disabled persons was summarized. Many investigators have found side effects of anticonvulsant drugs on vitamin D, calcium, folid acid, and vitamin B12 metabolism. Growth-retarding effects of certain central nervous system stimulants have also been reported. It has beed found that tranquilizers and antidepressant therapy show no effects on nutrient metabolism. Vitamins used in pharmacologic doses are considered as drugs; their therapeutic use was briefly reviewed here. The need for more research on biochemical interaction of drugs and nutrients was recommended.
总结了与据报道影响或不影响发育障碍者营养代谢及饮食的药物相关的文献。许多研究者发现抗惊厥药物对维生素D、钙、叶酸和维生素B12代谢有副作用。也有报道称某些中枢神经系统兴奋剂有生长迟缓作用。已发现镇静剂和抗抑郁治疗对营养代谢无影响。药理剂量使用的维生素被视为药物；在此简要回顾了它们的治疗用途。建议对药物与营养素的生化相互作用进行更多研究。
