Ylikorkala O
Ann Chir Gynaecol Fenn. 1975;64(4):242-5.
Twenty-five women suffering from climacteric complaints after surgical castration were treated with clonidine in a placebo controlled trial. Clonidine in the dose of 75 to 150 mug daily diminished the attack rates of flushing and sweating significantly. It can be recommended as a safe therapy for climacteric patients, at least those with contra-indications to oestrogen therapy.
在一项安慰剂对照试验中,对25名手术去势后出现更年期症状的女性使用可乐定进行治疗。每日剂量为75至150微克的可乐定可显著降低潮热和出汗的发作率。对于更年期患者,至少是那些有雌激素治疗禁忌症的患者,它可作为一种安全的治疗方法被推荐使用。