Lawrence D, Jablensky A V, Holman C D, Pinder T J
Centre for Health Services Research, Department of Public Health, The University of Western Australia, Nedlands, Australia.
Soc Psychiatry Psychiatr Epidemiol. 2000 Aug;35(8):341-7. doi: 10.1007/s001270050248.
The aim was to examine mortality in psychiatric patients in Western Australia (WA), over a time period of considerable change in the delivery of mental health services.
A population-based record linkage analysis was undertaken to quantify mortality among people with mental illness in WA. Mortality rates were calculated in users of mental health services and compared with rates in the whole population of WA. Trends in mortality were also examined using relative survival analysis, and proportional hazards regression.
The overall mortality rate ratio was 2.57 in males (95% CI: 2.51-2.64), and 2.18 in females (2.12-2.24). The highest cause-specific mortality rate ratio was for deaths due to suicide [RR: 7.37 in males (95% CI: 6.74-8.05) and 8.38 in females (95% CI: 7.11-9.89)], with mortality rate ratios being significantly greater than 1 for all other major causes of death. A relative survival analysis found that the excess mortality risk was concentrated in the first few years after first contact with mental health services. Proportional hazards regression analysis found a slight elevation of mortality rates over time.
Mortality among psychiatric patients remains high and appears to be increasing. Highest excess mortality rate is associated with suicide, but mortality rates are significantly elevated for all major causes of death.
目的是在西澳大利亚州(WA)心理健康服务提供发生重大变化的时间段内,研究精神病患者的死亡率。
进行了一项基于人群的记录链接分析,以量化WA州精神疾病患者的死亡率。计算了心理健康服务使用者的死亡率,并与WA州全体人口的死亡率进行比较。还使用相对生存分析和比例风险回归研究了死亡率趋势。
男性的总体死亡率比为2.57(95%可信区间:2.51 - 2.64),女性为2.18(2.12 - 2.24)。特定病因死亡率比最高的是自杀死亡[男性相对风险:7.37(95%可信区间:6.74 - 8.05),女性为8.38(95%可信区间:7.11 - 9.89)],所有其他主要死因的死亡率比均显著大于1。相对生存分析发现,额外的死亡风险集中在首次接触心理健康服务后的头几年。比例风险回归分析发现死亡率随时间略有上升。
精神病患者的死亡率仍然很高,而且似乎在上升。最高的额外死亡率与自杀有关,但所有主要死因的死亡率均显著升高。