多孔聚砜作为骨科和牙科植入物的附着载体。

Porous polysulfone as an attachment vehicle for orthopedic and dental implants.

作者信息

Ballintyn N J, Spector M

出版信息

Biomater Med Devices Artif Organs. 1979;7(1):23-9. doi: 10.3109/10731197909119369.

DOI:10.3109/10731197909119369

Abstract

The mechanical properties of porous polysulfone (PSF) were determined and its performance as a surface coating on orthopedic and dental implants evaluated. Ten coated femoral prostheses were implanted in nine dogs. A second series of four uncoated "control" prostheses and all of the acetabular cups were implanted using conventional bone cement techniques. Six porous PSF coated tooth roots were implanted in healed mandibular premolar extraction sites in three Rhesus monkeys. The shear strength of porous PSF (6 MPa) was comparable to that of trabecular bone. Pushout tests of 1cm. thick sections of the prostheses yielded interfacial shear strength values over 1.4 MPa for the PSF coated hips after 14 weeks and mean values under 0.7 MPa for the bone cemented specimens after 3 and 36 weeks. Bone and fibrous tissue was identified in the pores of coated specimens. Preliminary clinical evaluation of the functioning dental implants revealed zero mobility and other favorable clinical and radiographic indications after 2 months.

摘要

测定了多孔聚砜（PSF）的力学性能，并评估了其作为骨科和牙科植入物表面涂层的性能。将十个涂层股骨假体植入九只狗体内。使用传统骨水泥技术植入了第二批四个未涂层的“对照”假体以及所有髋臼杯。将六个多孔PSF涂层牙根植入三只恒河猴愈合的下颌前磨牙拔牙部位。多孔PSF的剪切强度（6MPa）与松质骨相当。对假体1cm厚的切片进行推出试验，14周后PSF涂层髋关节的界面剪切强度值超过1.4MPa，3周和36周后骨水泥固定标本的平均值低于0.7MPa。在涂层标本的孔隙中发现了骨组织和纤维组织。对功能性牙种植体的初步临床评估显示，两个月后活动度为零，并有其他良好的临床和影像学表现。