Fine R N, Offner G, Wilson W A, Mickey M R, Pennisi A F, Malekzadeh M H
Ann Surg. 1975 Nov;182(5):585-9. doi: 10.1097/00000658-197511000-00009.
Posterior subcapsular cataracts (PSC) were noted in 41 of 69 (60%) recipients of renal allografts. The PSC were noted during the first posttransplant year (Group 1) in 21 (30%) recipients and after the first posttransplant (Group 2) year in 20 (30%) recipients. The dosage of prednisone during the first posttransplant year corrected for patient weight showed a significant correlation with the development of PSC during the first posttransplant year. The severity of the PSC were correlated with time of onset and prednisone dosage. Four recipients in Group 1 required cataract extraction to obtain sufficient vision to facilitate school work.
在69例同种异体肾移植受者中,有41例(60%)出现后囊下白内障(PSC)。21例(30%)受者在移植后的第一年(第1组)出现PSC,20例(30%)受者在移植后的第一年之后(第2组)出现PSC。根据患者体重校正后的移植后第一年泼尼松剂量与移植后第一年PSC的发生显著相关。PSC的严重程度与发病时间和泼尼松剂量相关。第1组中有4例受者需要进行白内障摘除术以获得足够视力,以便于学业。