Limaye S R, Pillai S, Tina L U
Department of Ophthalmology, Georgetown University Medical Center, Washington, D.C.
Ann Ophthalmol. 1988 Jun;20(6):225-7.
Forty-five patients with nephrotic syndrome were included in our study. Of these, 30 received adrenocorticosteroid therapy and 15 did not. The ages of the patients ranged from 11 months to 27 years and the duration of steroid therapy from 2 1/2 years to 20 years. Seventeen patients (38%) showed posterior subcapsular cataract (PSC) formation and, of these, seven patients (41%) showed reversal of PSC. There was no statistical correlation between the total dose of steroids and the degree of PSC. An individual susceptibility may be an important factor in the production of PSC. None of the patients had visual acuity less than 20/30.
我们的研究纳入了45例肾病综合征患者。其中，30例接受了肾上腺皮质类固醇治疗，15例未接受。患者年龄从11个月至27岁不等，类固醇治疗时间从2.5年至20年不等。17例患者（38%）出现后囊下白内障（PSC）形成，其中7例患者（41%）的PSC出现逆转。类固醇的总剂量与PSC的程度之间无统计学相关性。个体易感性可能是PSC发生的一个重要因素。所有患者的视力均不低于20/30。
