肠致病性大肠杆菌O149:K91:H10的S型、R型和M型的毒性
[Toxicity of S-, R- and M-forms of enteropathogenic E. coli O149:K91:H10].
作者信息
Parnas J, Sorensen B
出版信息
Arch Exp Veterinarmed. 1975;29(4):531-49.
PMID:1103772
Abstract
Toxicity of freeze-dried lysates of the organism for unweaned mice (3-4 days old) increased in the order:smooth-mucoid-rough. The toxicity was neutralized by mixing the toxin with immune serum of group O149. All toxins of the smooth, rough and mucoid variants of the Escherichia coli strain possessed hypersensitivity, skin necrosis, abortion and diarrhoea factors, which could be partly or completely neutralized by binding with homologous immune serum.
摘要
该生物体冻干裂解物对未断奶小鼠（3 - 4日龄）的毒性按以下顺序增加：光滑型 - 黏液型 - 粗糙型。通过将毒素与O149群免疫血清混合可中和毒性。大肠杆菌菌株光滑型、粗糙型和黏液型变体的所有毒素均具有超敏反应、皮肤坏死、流产和腹泻因子，这些因子通过与同源免疫血清结合可部分或完全被中和。
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