Dodson K L, Coppo P A, Confer D L
National Marrow Donor Program, Minneapolis, Minnesota, USA.
Clin Transpl. 1999:121-7.
The National Marrow Donor Program has established a large and ethnically diverse registry of volunteer, unrelated stem cell donors. More than 9,000 patients world-wide have received transplants from NMDP donors. In recent years, substantial resources have been invested to increase that portion of the NMDP donor file with complete HLA-A, -B and -DR typing. While this effort has improved the likelihood of patients identifying a suitable matched unrelated donor, it has also focussed more attention on issues surrounding donor availability. Several initiatives underway or planned are intended to improve donor availability and increase the overall success of the unrelated donor stem cell transplantation.
国家骨髓捐赠项目已经建立了一个庞大且种族多样的志愿、非亲属干细胞捐赠者登记库。全球有超过9000名患者接受了来自该项目捐赠者的移植。近年来，已投入大量资源来增加国家骨髓捐赠项目捐赠者档案中具有完整 HLA - A、- B和 - DR分型的比例。虽然这一努力提高了患者找到合适匹配非亲属捐赠者的可能性，但也更加关注围绕捐赠者可及性的问题。正在进行或计划中的多项举措旨在提高捐赠者可及性，并提高非亲属捐赠者干细胞移植的总体成功率。
