Walker Tim, Milford Edgar, Chell Jeffery, Maiers Martin, Confer Dennis
National Marrow Donor Program, Minneapolis, Minnesota, USA.
Clin Transpl. 2011:55-62.
Since its founding in 1986, the NMDP has grown into a large international organization, providing patients with access to more than 9.5 million adult donors on the Be The Match Registry and to more than 18.5 million adult donors worldwide. Patients searching through the NMDP also have access to nearly 165,000 CBUs from NMDP-affiliated cord blood banks and nearly 600,000 CBUs worldwide. Through aggressive recruitment to the Be The Match Registry, and by establishing connections to international registries, the NMDP gives patients in need of a transplant access to a large and diverse pool of unrelated donors and CBUs. This has resulted in a steady increase in the likelihood of finding a matching donor or CBU for searching patients of all races/ethnicities. The NMDP has also developed programs and initiatives that have successfully increased the efficiency of the search process, which has decreased the time to transplant. The NMDP has also developed strategies that have improved access to transplant, especially among minority racial/ethnic patient populations. These long-standing and ongoing efforts to grow the Be The Match Registry and to improve the search process resulted in a record number of NMDP-facilitated transplants in 2011--more than 5,500--and now have facilitated more than 50,000 transplants since 1986. However, the NMDP, using SEER data, has calculated that there are approximately 10,000 patients in the U.S. each year who could potentially benefit from unrelated donor HCT. The NMDP has therefore set a goal to facilitate 10,000 transplants annually. Although meeting this goal will require nearly doubling the annual rate of transplants, the NMDP is confident that it has the expertise, personnel, facilities, and commitment to achieve this goal.
自1986年成立以来，国家骨髓捐赠项目（NMDP）已发展成为一个大型国际组织，为患者提供了“成为配型者”登记库中950多万成年捐赠者以及全球1850多万成年捐赠者的信息。通过NMDP进行搜索的患者还可以获取来自NMDP附属脐带血库的近16.5万份脐带血单位以及全球近60万份脐带血单位的信息。通过积极招募加入“成为配型者”登记库，并与国际登记库建立联系，NMDP使需要移植的患者能够接触到大量且多样化的无关捐赠者和脐带血单位。这使得为所有种族/族裔的搜索患者找到匹配捐赠者或脐带血单位的可能性稳步增加。NMDP还制定了一些项目和举措，成功提高了搜索过程的效率，从而缩短了移植时间。NMDP还制定了一些策略，改善了移植的可及性，尤其是在少数种族/族裔患者群体中。这些长期持续的努力，旨在扩大“成为配型者”登记库并改进搜索过程，使得2011年由NMDP促成的移植数量创下纪录——超过5500例——自1986年以来已促成了超过50000例移植。然而，NMDP利用监测、流行病学与最终结果（SEER）数据计算得出，美国每年约有10000名患者可能从无关供体造血细胞移植中受益。因此，NMDP设定了每年促成10000例移植的目标。尽管要实现这一目标需要将年移植率几乎提高一倍，但NMDP相信自己具备实现这一目标所需的专业知识、人员、设施和决心。
