Zamir G A, Olthoff K M, Nunes F A, Markmann J F, Zeldin G A, Stewart C A, Weinreib R M, Rand E B, Maller E S, Lucey M R, Shaked A
Department of Medicine, University of Pennsylvania, Philadelphia, USA.
Clin Transpl. 1999:223-9.
The liver transplant program at the University of Pennsylvania and the Children's Hospital of Philadelphia experienced healthy growth in its clinical activity in the past 5 years. Patterns of referral and patient evaluation were established, care of patients while waiting on the list or being followed after transplantation was streamlined. We are now achieving excellent outcomes while transplanting relatively sicker patients. Innovative surgical procedures are implemented resulting in more efficient utilization of cadaveric and living-donor liver grafts. The protocols that are used for patient care are more standard, yet flexible and accommodate recent advancement in transplantation immunobiology. This progress of the clinical program was enhanced by careful preservation of the academic mission of the institution, which encourages the liver transplant faculty to be involved in NIH-supported clinical and basic science research.
宾夕法尼亚大学和费城儿童医院的肝移植项目在过去5年中临床活动实现了稳健增长。建立了转诊和患者评估模式，优化了患者在等待名单上时的护理以及移植后的随访。我们现在在为病情相对较重的患者进行移植时也能取得优异的成果。实施了创新的外科手术，提高了尸体供肝和活体供肝的利用效率。用于患者护理的方案更加标准化，但又灵活且能适应移植免疫生物学的最新进展。该机构对学术使命的精心维护推动了临床项目的这一进展，这鼓励肝移植团队参与由美国国立卫生研究院资助的临床和基础科学研究。
