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[Effect of ofloxacin, pefloxacin, and tobramycin on the hydrophobicity of Klebsiella pneumoniae].

作者信息

Hostacká A

机构信息

Ustav preventívnej a klinickej medicíny, Bratislava.

出版信息

Epidemiol Mikrobiol Imunol. 1999 Feb;48(1):28-30.

PMID:11038674
Abstract

The effect of ofloxacin, pefloxacin and tobramycin at subinhibitory concentrations (1/4, 1/8 and 1/16 of the MICs) on surface hydrophobicity of the Klebsiella pneumoniae strain was studied. The antibiotics tested decreased cell surface hydrophobicity in a dose-dependent manner. The most significant reduction of surface hydrophobicity was found after treatment with antibiotics at 1/4 of their MICs. Surface hydrophobicity of K. pneumoniae after exposure to these concentrations was decreased to 44% (ofloxacin), 50.7% (pefloxacin) and 56.1% (tobramycin) compared with controls.

摘要

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