Liu P, Tao S, Xia K
First Affiliated Hospital, Nanjing Medical University.
Zhonghua Zhong Liu Za Zhi. 1997 Jul;19(4):313-5.
To summarize the experience in the diagnosis and treatment of giant-cell tumor of bone, the selection of various operation methods and their effects were evaluated and discussed.
From 105 cases of giant-cell tumor of bone data were collected and reviewed. The clinical features were analyzed in association with radiological and histological characteristics. Prognosis was assessed by long-term follow-up.
Among 105 cases, one had multiple giant-cell tumors and two had distant metastases. In some cases, the radiological and histological appearances didn't accord with the clinical findings. The recurrence rate was 36% in patients treated with curettage. Although no recurrence was seen in patients treated by local excision, the joint function could not be fully retained.
Diagnosis should be made on the basis of integrated clinical, radiological and pathological manifestations. Early diagnosis and operation are important. The function of joint must be retained as much as possible. Pre-operative embolization of tumor of sacrum and pelvis is very helpful to ensure operative success and to minimize recurrence.
总结骨巨细胞瘤的诊断与治疗经验，对各种手术方法的选择及其效果进行评估与讨论。
收集并回顾105例骨巨细胞瘤病例资料。结合影像学和组织学特征分析临床特点。通过长期随访评估预后。
105例中，1例为多发骨巨细胞瘤，2例有远处转移。部分病例影像学和组织学表现与临床不符。刮除术治疗患者的复发率为36%。局部切除术治疗患者虽未见复发，但关节功能不能完全保留。
应综合临床、影像学和病理表现进行诊断。早期诊断和手术很重要。应尽可能保留关节功能。骶骨和骨盆肿瘤的术前栓塞对确保手术成功及减少复发非常有帮助。
