Zhou J W
Huashan Hospital, Shanghai Medical College.
Zhonghua Zhong Liu Za Zhi. 1990 Sep;12(5):389-91.
Fifty cases of giant cell tumor of bone are reported in this paper. The peak age was 20-40 years (76%). 75% of the tumors occurred in the extremity of long bones, of which 36% were around the knee. These patients were treated by curettage and bone graft or bone cement filling, bloc resection with or without bone graft and amputation. In this series, the follow-up time was 4 months-22 years and 3 months, and recurrence rate was 34%. There was no marked relation between recurrence and grade of tumor (35% for Grade I, 31% for Grade II and 25% for 25% Grade III). Patients with Grade III tumor had much poorer prognosis than those with Grade I or II. The surgical treatment of giant cell tumor of bone, particularly tumor of the spine, is still a challenge for orthopedic surgeons. Bloc resection of the tumor might be the treatment of choice for giant cell tumor of bone.
本文报告了50例骨巨细胞瘤。发病高峰年龄为20 - 40岁（占76%）。75%的肿瘤发生于长骨末端，其中36%位于膝关节周围。这些患者接受了刮除植骨或骨水泥填充、带或不带植骨的整块切除以及截肢治疗。本系列中，随访时间为4个月至22年3个月，复发率为34%。复发与肿瘤分级之间无明显关系（I级为35%，II级为31%，III级为25%）。III级肿瘤患者的预后比I级或II级患者差得多。骨巨细胞瘤的手术治疗，尤其是脊柱肿瘤的手术治疗，对骨科医生来说仍然是一项挑战。肿瘤整块切除可能是骨巨细胞瘤的首选治疗方法。
