Wu S, Han Y, Li J
First Affiliated Hospital of Tianjin College of TCM.
J Tradit Chin Med. 2000 Sep;20(3):172-5.
It is the view of the authors that accumulation of heat and dampness in the heart and stomach and deficiency of both spleen and kidney with blood stasis would be the main predisposing factors in pathogenesis of incipient diabetic nephropathy. A controlled clinical study of 32 patients treated with modified recipe of Wang Kentang's Bai Fu Ling Wan, a proved formula of clearing away the stomach-heat, purging the heart fire, strengthening the stomach and tonifying the kidney, and simultaneously resolving blood stasis and turbid qi was performed. The total effective rate was 93.8%, superior to that in the control group treated with Capoton (59.9%). A marked improvement in symptoms, control of blood glucose level and reduction of urinary protein obtained in the treatment group suggests that this treatment is effective in retarding the development of the disease.
作者认为，心胃湿热、脾肾两虚兼血瘀是早期糖尿病肾病发病的主要诱发因素。对32例患者进行了一项对照临床研究，采用王肯堂白茯苓丸的改良配方进行治疗，该配方是一个经证实的方剂，具有清胃热、泻心火、健胃补肾，同时化瘀浊之气的功效。总有效率为93.8%，优于用卡托普利治疗的对照组（59.9%）。治疗组症状明显改善、血糖水平得到控制、尿蛋白减少，表明该治疗方法在延缓疾病发展方面有效。
