四苯基硼对酵母细胞摄取亲脂性阳离子二苄基二甲基铵的影响。

Effect of tetraphenylboron upon the uptake of the lipophilic cation dibenzyldimethylammonium by yeast cells.

作者信息

Hoeberichts J A, Borst-Pauwels G W

出版信息

Biochim Biophys Acta. 1975 Dec 1;413(2):248-51. doi: 10.1016/0005-2736(75)90109-1.

Abstract

The rate of uptake of the lipophilic cation dibenzyldimethylammonium by yeast cells is increased by tetraphenylboron. However, tetraphenylboron increases also the equilibrium partition of dibenzyldimethylammonium between cells and medium, probably because a complex between tetraphenylboron and dibenzyldimethylammonium is trapped inside the cells. Accumulation of dibenzyldimethylammonium in the presence of tetraphenylboron is not reversed by dinitrophenol, whereas accumulation of the lipophilic cation in the absence of tetraphenylboron appears to be almost completely reversible.

摘要

酵母细胞对亲脂性阳离子二苄基二甲基铵的摄取速率会因四苯基硼而增加。然而，四苯基硼也会增加二苄基二甲基铵在细胞与培养基之间的平衡分配，这可能是因为四苯基硼与二苄基二甲基铵之间形成的复合物被困在了细胞内。在四苯基硼存在的情况下，二苄基二甲基铵的积累不会被二硝基苯酚逆转，而在没有四苯基硼的情况下，亲脂性阳离子的积累似乎几乎是完全可逆的。