Lee S, Milner A D
Newborn Respiratory Unit, Department of Paediatrics, 4th floor, North Wing, St Thomas' Hospital, London SE1 7EH, UK.
Arch Dis Child Fetal Neonatal Ed. 2000 Nov;83(3):F203-6. doi: 10.1136/fn.83.3.f203.
To observe how the resonance frequency changes with the course of respiratory distress syndrome (RDS), by examining the effect of changing static compliance on the resonance frequency in premature infants.
In 12 ventilated premature infants with RDS (mean gestational age 26.6 weeks, mean birth weight 0.84 kg), resonance frequency and static compliance were determined serially using phase analysis and single breath mechanics technique respectively in the first seven days of life.
The minimum number of measurements done in any one baby was three and maximum was five in this seven day study period. The first measurement in each baby was done within the first 72 hours of life. The increase in compliance in this period varied from 27% to 179%. The variation in the corresponding resonance frequency was within 2 Hz in eight babies and within 6 Hz in all recruited babies.
The resonance frequency of the respiratory system in preterm infants with RDS remains remarkably constant in the early stages of the illness, despite relatively large changes in static compliance.
通过研究改变静态顺应性对早产儿呼吸频率的影响,观察呼吸窘迫综合征(RDS)病程中呼吸频率如何变化。
对12例患有RDS的机械通气早产儿(平均胎龄26.6周,平均出生体重0.84kg),在出生后7天内分别采用相位分析和单次呼吸力学技术连续测定呼吸频率和静态顺应性。
在这7天的研究期间,每个婴儿进行测量的最少次数为3次,最多为5次。每个婴儿的首次测量在出生后72小时内完成。在此期间,顺应性增加幅度在27%至179%之间。8例婴儿相应呼吸频率的变化在2Hz以内,所有纳入婴儿的呼吸频率变化在6Hz以内。
患有RDS的早产儿呼吸系统的呼吸频率在疾病早期保持显著稳定,尽管静态顺应性有较大变化。