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锝99闪烁扫描术在四肢严重冻伤截肢预后评估中的价值:一项对92例严重冻伤病例的回顾性研究

The value of technetium 99 scintigraphy in the prognosis of amputation in severe frostbite injuries of the extremities: A retrospective study of 92 severe frostbite injuries.

作者信息

Cauchy E, Marsigny B, Allamel G, Verhellen R, Chetaille E

机构信息

Department of Mountain Medicine and Trauma, Chamonix Hospital, Chamonix, France.

出版信息

J Hand Surg Am. 2000 Sep;25(5):969-78. doi: 10.1053/jhsu.2000.16357.

Abstract

We report a retrospective study of the prognostic value of 2-phase technetium 99m bone scanning performed in 92 patients who presented to Chamonix Hospital with severe frostbite of the extremities in the past 12 years. The results of this study show that an initial bone scan (as early as day 3) has excellent specificity in evaluating the severity of frostbite injury. There was a direct correlation between the demarcation zone of uptake in the phalanges and the eventual level of amputation (positive predictive value, 0.84). A second scan on approximately day 7 was even more sensitive and informative. A strong correlation existed between positive uptake and eventual healing (negative predictive value, 0.99). This study showed that (99m)Tc bone scanning in the first few days after frostbite injury indicates the level of amputation in severe frostbite in more than 84% of cases. We propose an algorithm based on the results of this study that can be used to evaluate new medical and surgical management of frostbite injury.

摘要

我们报告了一项回顾性研究,该研究针对过去12年中因四肢严重冻伤而就诊于夏蒙尼医院的92例患者进行了两阶段锝99m骨扫描的预后价值评估。这项研究结果表明,初始骨扫描(最早在第3天)在评估冻伤损伤严重程度方面具有出色的特异性。指骨摄取分界区与最终截肢水平之间存在直接相关性(阳性预测值为0.84)。大约在第7天进行的第二次扫描甚至更敏感且信息丰富。阳性摄取与最终愈合之间存在强烈相关性(阴性预测值为0.99)。这项研究表明,冻伤损伤后最初几天的锝99m骨扫描在超过84%的严重冻伤病例中可指示截肢水平。我们基于这项研究结果提出了一种算法,可用于评估冻伤损伤的新医疗和手术管理方法。

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