Manganaro Matthew S, Millet John D, Brown Richard Kj, Viglianti Benjamin L, Wale Daniel J, Wong Ka Kit
1 Departments of Radiology/Nuclear Medicine, University of Michigan Hospital , Ann Arbor, MI , USA.
2 Nuclear Medicine Service, VA Ann Arbor Healthcare , Ann Arbor, MI , USA.
Br J Radiol. 2019 Feb;92(1094):20180545. doi: 10.1259/bjr.20180545. Epub 2018 Nov 1.
: Frostbite is a localized cold-thermal injury resulting from prolonged exposure of flesh to freezing and near freezing temperatures. The depth and extent of frostbite injuries are not easily assessed, from a clinical standpoint, at the time of injury making it challenging to plan appropriate management and treatment.
: A review of the literature of management of cold-related injuries and retrospective case review of the imaging and clinical course of frostbite injury.
: Bone scintigraphy with single photon emission computed tomography (SPECT)/CT was performed in the acute and subacute course of frostbite injuries, subsequently leading to earlier definitive management and shorter hospital stay.
: Multiphase technetium-99m-methylenediphosphonate (mTc-MDP) bone scintigraphy with SPECT/CT can expedite clinical management of frostbite injuries by determining the extent of injury and can accurately predict the level of amputation if needed.
: SPECT/CT is underutilized at many facilities but can have a profound and immediate impact on clinical management of patients with frostbite when used in combination with physiological bone scan imaging.
冻伤是由于身体长时间暴露于冰点及接近冰点温度下所导致的局部冷损伤。从临床角度来看，在受伤时冻伤损伤的深度和范围不易评估，这使得规划适当的管理和治疗具有挑战性。
回顾与寒冷相关损伤管理的文献，并对冻伤损伤的影像学和临床过程进行回顾性病例分析。
在冻伤损伤的急性期和亚急性期进行了单光子发射计算机断层扫描（SPECT）/CT骨闪烁显像，随后实现了更早的确定性管理并缩短了住院时间。
采用SPECT/CT的多相锝-99m-亚甲基二膦酸盐（mTc-MDP）骨闪烁显像可通过确定损伤程度来加快冻伤损伤的临床管理，并且在需要时能够准确预测截肢水平。
SPECT/CT在许多机构未得到充分利用，但与生理性骨扫描成像联合使用时，可对冻伤患者的临床管理产生深远且即时的影响。
