Kuroteva Z V, Baĭler L M, Zhumabaeva T T
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia.
Biofizika. 2000 Jul-Aug;45(4):671-4.
The effect of ascorbic acid on suspensions of blood formic elements was studied by the ESR method. It was shown that incubation of a suspension of formic blood elements in the presence of ascorbic acid leads to the appearance of nitric oxide, which is produced by leukocytes and partially probably by thrombocytes. The formation of nitric oxide is evidenced by the appearance of nitrosyl complexes heme-NO. In this case, hemoglobin of erythrocytes serves as a natural trap for nitric oxide.
采用电子自旋共振（ESR）方法研究了抗坏血酸对血液有形成分悬浮液的影响。结果表明，在抗坏血酸存在的情况下孵育有形成分悬浮液会导致一氧化氮的出现，一氧化氮由白细胞产生，部分可能由血小板产生。亚硝酰络合物血红素-NO的出现证明了一氧化氮的形成。在这种情况下，红细胞中的血红蛋白充当一氧化氮的天然捕获剂。
