Kuropteva Z V, Kudryavtsev M E
Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia.
Gen Physiol Biophys. 1997 Mar;16(1):91-6.
Ferrous-ascorbate is known to form with nitric oxide paramagnetic nitrosyl ferrous-ascorbate complexes, Fe-AA-NO. These complexes yield on EPR signal with g-factor close to 2.02 and an optical absorption spectrum with maxima at 340, 460, and 600 nm. Fe-AA-NO complexes are unstable in the presence of oxygen. Ferrous-ascorbate complexes promote NaNO2 decay resulting in the formation of NO. Nitric oxide is taken up by Fe-AA complexes to form paramagnetic ferrous-ascorbate nitrosyl complexes, Fe-AA-NO. It is suggested that ferrous-ascorbate complexes can play the role of carriers of NO and, perhaps, O2 in the blood plasma. Nitrosyl ferrous-ascorbate complexes can also be the NO containing factor involved in the blood vessel relaxation (endothelium-derived relaxing factor, EDRF).
已知抗坏血酸亚铁与一氧化氮形成顺磁性亚硝酰基抗坏血酸亚铁配合物Fe-AA-NO。这些配合物产生g因子接近2.02的电子顺磁共振信号和在340、460和600nm处有最大值的光吸收光谱。Fe-AA-NO配合物在氧气存在下不稳定。抗坏血酸亚铁配合物促进NaNO₂分解，导致NO形成。一氧化氮被Fe-AA配合物吸收形成顺磁性亚硝酰基抗坏血酸亚铁配合物Fe-AA-NO。有人提出，抗坏血酸亚铁配合物可以在血浆中充当NO甚至O₂的载体。亚硝酰基抗坏血酸亚铁配合物也可能是参与血管舒张的含NO因子（内皮源性舒张因子，EDRF）。
