锂诱导大鼠垂体神经叶中神经胶质细胞在体内的增殖。
Proliferation of glial cells in vivo induced in the neural lobe of the rat pituitary by lithium.
作者信息
Levine S, Saltzman A, Klein A W
机构信息
Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA.
出版信息
Cell Prolif. 2000 Aug;33(4):203-7. doi: 10.1046/j.1365-2184.2000.00170.x.
Abstract
Lithium salts are widely used for treatment of psychiatric illness. Lithium also affects cell proliferation. During investigation of the effect of lithium chloride on the central nervous system (CNS) of nephrectomized rats, we noted numerous mitotic figures in the neural lobe of the pituitary. Morphologic criteria established that the mitotic cells were astrocytes, the supporting glial cells of the CNS, also known as pituicytes. Equimolar doses of chlorides of chemically related cations (sodium, potassium, rubidium) had no such effect.
摘要
锂盐被广泛用于治疗精神疾病。锂也会影响细胞增殖。在研究氯化锂对肾切除大鼠中枢神经系统（CNS）的作用时，我们注意到垂体神经叶中有许多有丝分裂图像。形态学标准确定有丝分裂细胞是星形胶质细胞，即中枢神经系统的支持性神经胶质细胞，也称为垂体细胞。等摩尔剂量的化学相关阳离子（钠、钾、铷）的氯化物没有这种作用。
相似文献
1
Proliferation of glial cells in vivo induced in the neural lobe of the rat pituitary by lithium.锂诱导大鼠垂体神经叶中神经胶质细胞在体内的增殖。
Cell Prolif. 2000 Aug;33(4):203-7. doi: 10.1046/j.1365-2184.2000.00170.x.
2
Proliferation of glial cells induced by lithium in the neural lobe of the rat pituitary is enhanced by dehydration.锂诱导的大鼠垂体神经叶中胶质细胞的增殖因脱水而增强。
Cell Prolif. 2002 Jun;35(3):167-72. doi: 10.1046/j.1365-2184.2002.00235.x.
3
Mitotic figures in the median eminence of the hypothalamus.下丘脑正中隆起有丝分裂象。
Neurochem Res. 2010 Nov;35(11):1743-6. doi: 10.1007/s11064-010-0237-9. Epub 2010 Aug 1.
4
The effects of long-term administration of rubidium or lithium on reactivity to stress and on dopamine output in the nucleus accumbens in rats.长期给予铷或锂对大鼠应激反应性及伏隔核多巴胺释放量的影响。
Brain Res. 1999 May 1;826(2):200-9. doi: 10.1016/s0006-8993(99)01286-x.
5
The myoneural effects of lithium chloride on the nerve-muscle preparations of rats. Role of adenosine triphosphate-sensitive potassium channels.氯化锂对大鼠神经肌肉标本的肌神经效应。三磷酸腺苷敏感性钾通道的作用。
Pharmacol Res. 2000 Feb;41(2):163-78. doi: 10.1006/phrs.1999.0574.
6
A low dose of lithium chloride selectively induces Fos protein in the central nucleus of the amygdala of rat brain.
Prog Neuropsychopharmacol Biol Psychiatry. 2000 Feb;24(2):285-94. doi: 10.1016/s0278-5846(99)00092-5.
7
Alterations induced by lithium in gfap expression and in the proteinic composition of glial cells in vitro.
Rom J Physiol. 2000 Jan-Dec;37(1-4):81-9.
8
Lithium increases body weight of rats: relation to thymolysis.
Prog Neuropsychopharmacol Biol Psychiatry. 2006 Jan;30(1):155-8. doi: 10.1016/j.pnpbp.2005.08.023. Epub 2005 Oct 18.
9
Proteomic analysis of lithium-induced gene expression in the rat hypothalamus.锂诱导大鼠下丘脑基因表达的蛋白质组学分析。
Int J Neurosci. 2009;119(9):1267-81. doi: 10.1080/00207450902889201.
10
Glial cell line-derived neurotrophic factor in the rat pituitary gland.
Brain Res Bull. 2000 May 15;52(2):109-13. doi: 10.1016/s0361-9230(00)00242-2.
引用本文的文献
1
Cellular abnormalities in depression: evidence from postmortem brain tissue.抑郁症中的细胞异常：来自尸检脑组织的证据。
Dialogues Clin Neurosci. 2004 Jun;6(2):185-97. doi: 10.31887/DCNS.2004.6.2/cstockmeier.
2
Mitotic figures in the median eminence of the hypothalamus.下丘脑正中隆起有丝分裂象。
Neurochem Res. 2010 Nov;35(11):1743-6. doi: 10.1007/s11064-010-0237-9. Epub 2010 Aug 1.
3
Proliferation of glial cells induced by lithium in the neural lobe of the rat pituitary is enhanced by dehydration.锂诱导的大鼠垂体神经叶中胶质细胞的增殖因脱水而增强。
Cell Prolif. 2002 Jun;35(3):167-72. doi: 10.1046/j.1365-2184.2002.00235.x.
本文引用的文献
1
The relationship of the pituicyte to the posterior lobe hormones.垂体细胞与后叶激素的关系。
Endocrinology. 1959 Dec;65:909-15. doi: 10.1210/endo-65-6-909.
2
Carbohydrate diet prolongs survival of rats with acute uremia after bilateral nephrectomy.
Nephron. 1997;77(2):242-3. doi: 10.1159/000190282.
3
Dehydration-induced proliferation of identified pituicytes in fully adult rats.
Glia. 1995 Sep;15(1):65-76. doi: 10.1002/glia.440150108.
4
Microglial responses to physiological change: osmotic stress elevates DNA synthesis of neurohypophyseal microglia.小胶质细胞对生理变化的反应：渗透压应激会提高神经垂体小胶质细胞的DNA合成。
Neuroscience. 1993 Oct;56(4):929-38. doi: 10.1016/0306-4522(93)90139-7.
5
Ultrastructural changes and proliferation of pituicytes in mouse posterior lobe during water deprivation and rehydration.缺水及再水化过程中小鼠垂体后叶垂体细胞的超微结构变化及增殖
Acta Anat (Basel). 1984;119(3):136-41. doi: 10.1159/000145875.
6
Changes in the volume of the lobes of the pituitary gland and in the weight and water content of organs of rats given hypertonic saline.
J Endocrinol. 1968 Aug;41(4):593-600. doi: 10.1677/joe.0.0410593.
7
Effects of dehydration on the rate of proliferation of hypothalamic neuroglia cells.
Exp Neurol. 1968 Mar;20(3):460-8. doi: 10.1016/0014-4886(68)90087-3.
8
The proliferation of astrocytes around a needle wound in the rat brain.
J Anat. 1970 May;106(Pt 3):471-87.
9
Extracellular potassium influences DNA and protein syntheses and glial fibrillary acidic protein expression in cultured glial cells.
Glia. 1990;3(5):368-74. doi: 10.1002/glia.440030508.
10
Increased proliferation of neuroglia and endothelial cells in the supraoptic nucleus and hypophysial neural lobe of young rats drinking hypertonic sodium chloride solution.饮用高渗氯化钠溶液的幼鼠视上核和垂体神经叶中神经胶质细胞和内皮细胞的增殖增加。
J Comp Neurol. 1977 Oct 15;175(4):373-90. doi: 10.1002/cne.901750402.
Zotero 插件