Cowper S E, Robin H S, Steinberg S M, Su L D, Gupta S, LeBoit P E
Lancet. 2000 Sep 16;356(9234):1000-1. doi: 10.1016/S0140-6736(00)02694-5.
15 renal dialysis patients have been identified with a skin condition characterised by thickening and hardening of the skin of the extremities and an increase in dermal fibroblast-like cells associated with collagen remodelling and mucin deposition. The disease closely resembles scleromyxoedema, yet has significant enough clinical and histopathological differences to warrant its designation as a new clinicopathological entity.
已确定15名肾透析患者患有一种皮肤病，其特征为四肢皮肤增厚、硬化，与胶原重塑和黏蛋白沉积相关的真皮成纤维细胞样细胞增多。该疾病与硬化性黏液水肿极为相似，但在临床和组织病理学上存在足够显著的差异，足以将其认定为一种新的临床病理实体。
