Shcherba V V, Babitskaia V G, Kurchenko V P, Ikonnikova N V, Kukulianskaia T A
Institute of Microbiology, Belarussian Academy of Sciences, Minsk, Belarus.
Prikl Biokhim Mikrobiol. 2000 Sep-Oct;36(5):569-74.
Fungal melanin pigments were shown to display a high antioxidant activity. An increase in the number of methyl substituents in benzidine molecules of melanins obtained from micromycetes and macromycetes was accompanied by a decrease in the efficiency of inhibition of peroxidase-catalyzed oxidation. Melanins were found to have considerable gene-protecting properties. Pigments isolated from macromycetes and applied at a much lower concentration than those obtained from micromycetes prevented damage to bacteriophage-lambda DNA induced by products of peroxidase-catalyzed degradation of aminobiphenyls.