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[Antioxidant features of fungal melanin pigments].

作者信息

Shcherba V V, Babitskaia V G, Kurchenko V P, Ikonnikova N V, Kukulianskaia T A

机构信息

Institute of Microbiology, Belarussian Academy of Sciences, Minsk, Belarus.

出版信息

Prikl Biokhim Mikrobiol. 2000 Sep-Oct;36(5):569-74.

Abstract

Fungal melanin pigments were shown to display a high antioxidant activity. An increase in the number of methyl substituents in benzidine molecules of melanins obtained from micromycetes and macromycetes was accompanied by a decrease in the efficiency of inhibition of peroxidase-catalyzed oxidation. Melanins were found to have considerable gene-protecting properties. Pigments isolated from macromycetes and applied at a much lower concentration than those obtained from micromycetes prevented damage to bacteriophage-lambda DNA induced by products of peroxidase-catalyzed degradation of aminobiphenyls.

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