Caccia M R
Eur Neurol. 1975;13(6):560-3. doi: 10.1159/000114712.
Clonazepam seems to be an effective drug in idiopathic trigeminal neuralgia. Electrophysiological investigations support the idea that this neuralgia is due to a loss of central inhibition. During the first 1-2 weeks of treatment marked drowsiness is observed in the majority of cases. In one case, presence of a synergism between Clonazepam and L-dopa+ inhibitor was also observed.
氯硝西泮似乎是治疗特发性三叉神经痛的一种有效药物。电生理研究支持这样一种观点,即这种神经痛是由于中枢抑制作用丧失所致。在治疗的最初1 - 2周内,大多数病例会出现明显的嗜睡症状。有一例还观察到氯硝西泮与左旋多巴+抑制剂之间存在协同作用。