日本隐睾男性雄激素受体基因的CAG重复长度
CAG repeat length of the androgen receptor gene in Japanese males with cryptorchidism.
作者信息
Sasagawa I, Suzuki Y, Tateno T, Nakada T, Muroya K, Ogata T
机构信息
Department of Urology, Yamagata University School of Medicine, Yamagata, Japan.
出版信息
Mol Hum Reprod. 2000 Nov;6(11):973-5. doi: 10.1093/molehr/6.11.973.
We have analysed the CAG repeat length in exon 1 of the androgen receptor gene in 48 Japanese males with cryptorchidism and 100 fertile Japanese males. The CAG repeat length was 23.4 +/- 0.48 (mean +/- SE) (range 16-32, median 23) in cryptorchid patients and 23.5 +/- 0.29 (range 15-32, median 23) in normal males. There was no significant difference between the two groups. The expansion of the CAG repeats in exon 1 of the androgen receptor gene is unlikely to constitute a major cause of cryptorchidism.
我们分析了48名患有隐睾症的日本男性和100名具有生育能力的日本男性雄激素受体基因外显子1中的CAG重复序列长度。隐睾症患者的CAG重复序列长度为23.4±0.48（平均值±标准误）（范围16 - 32，中位数23），正常男性为23.5±0.29（范围15 - 32，中位数23）。两组之间无显著差异。雄激素受体基因外显子1中CAG重复序列的扩增不太可能是隐睾症的主要原因。
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