Heller D S, Hessami S, Cracchiolo B, Skurnick J H
Department of Pathology-UH/E141, UMDNJ-New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA.
J Am Assoc Gynecol Laparosc. 2000 Nov;7(4):519-22. doi: 10.1016/s1074-3804(05)60366-0.
To assess the accuracy of frozen section evaluation of uterine curettings to look for chorionic villi and rule out ectopic pregnancy before laparoscopy.
Retrospective review (Canadian Task Force classification III).
Northeastern medical school-affiliated teaching hospital.
Thirty-six women. Intervention. Dilatation and curettage, laparoscopy, and laparotomy.
Of 36 cases, 13 showed evidence of intrauterine pregnancy, either chorionic villi or implantation site, on final permanent sections. Five false negatives were identified in which no villi were identified on frozen section, although villi or evidence of an implantation site was noted on permanent sections (sensitivity 62%, 95% CI 0.32, 0.86).
Frozen section evaluation of uterine curettings can produce false negative diagnoses, and this should be considered in the operative planning of women with suspected ectopic pregnancy.
评估刮宫组织冰冻切片检查寻找绒毛膜绒毛的准确性，并在腹腔镜检查前排除异位妊娠。
回顾性研究（加拿大工作组分类III级）。
东北部医学院附属教学医院。
36名女性。干预措施：刮宫术、腹腔镜检查和剖腹手术。
36例病例中，13例在最终的永久性切片上显示有宫内妊娠的证据，即绒毛膜绒毛或着床部位。发现5例假阴性病例，这些病例在冰冻切片上未发现绒毛，但在永久性切片上发现了绒毛或着床部位的证据（敏感性62%，95%可信区间0.32，0.86）。
刮宫组织的冰冻切片检查可能会产生假阴性诊断，在疑似异位妊娠女性的手术规划中应考虑到这一点。
