Kraml P, Potocková J, Andĕl M, Zvárová J, Stefek M
II. interní klinika FNKV a 3. lékarské fakulty UK, Praha.
Vnitr Lek. 1999 Aug;45(8):457-62.
Incidence of atherosclerotic cardiovascular diseases in diabetics is known to be 2-4 times higher than in nondiabetic subjects. Intima-media-thickness of common carotid artery (IMT ACC) measured by B-mode sonography positively correlates with the severity of atherosclerotic changes in coronary arteries. This study compares sonographically assessed IMT ACC in patients with type 2 diabetes mellitus (27 patients, mean age 66.57 +/- 6.06 years) vs. 66 nondiabetic subjects (mean age 63.58 +/- 9.09 years). Intima-media thickness in diabetics was significantly higher when compared with the control group (0.826 +/- 0.29 mm vs. 0.647 +/- 0.26 mm). In the whole cohort of investigated subjects IMT ACC positively correlates with age. When adjusted for age, the mean IMT ACC level was significantly higher in men than in women.
已知糖尿病患者发生动脉粥样硬化性心血管疾病的几率比非糖尿病患者高2至4倍。通过B型超声测量的颈总动脉内膜中层厚度(IMT ACC)与冠状动脉粥样硬化病变的严重程度呈正相关。本研究比较了经超声检查评估的2型糖尿病患者(27例,平均年龄66.57±6.06岁)与66例非糖尿病受试者(平均年龄63.58±9.09岁)的IMT ACC。与对照组相比,糖尿病患者的内膜中层厚度明显更高(0.826±0.29毫米对0.647±0.26毫米)。在整个研究对象队列中,IMT ACC与年龄呈正相关。在调整年龄因素后,男性的平均IMT ACC水平显著高于女性。